Taking aim on bacterial pathogens: from phage therapy to enzybiotics

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Taking aim on bacterial pathogens: from phage therapy to enzybiotics.

The bactericidal activity of bacteriophages has been used to treat human infections for years as an alternative or a complement to antibiotic therapy. Nowadays, endolysins (phage-encoded enzymes that break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle) have been used successfully to control antibiotic-resistant pathogenic bacteria in animal models. Their cel...

متن کامل

Taking aim at translation for tumor therapy.

Increased cap-dependent mRNA translation rates are frequently observed in human cancers. Mechanistically, many human tumors often overexpress the cap binding protein eukaryotic translation initiation factor 4E (eIF4E), leading to enhanced translation of numerous tumor-promoting genes. In this issue of the JCI, Graff and colleagues describe potent antitumor effects using second-generation antise...

متن کامل

Phage-based detection of bacterial pathogens.

Bacterial pathogens cause significant morbidity and mortality annually to both humans and animals. With the rampant spread of drug resistance and the diminishing effectiveness of current antibiotics, there is a pressing need for effective diagnostics for detection of bacterial pathogens and their drug resistances. Bacteriophages offer several unique opportunities for bacterial detection. This r...

متن کامل

Biocontrol of Bacterial Pathogens in Aquaculture with Emphasis on Phage Therapy

Loss due to diseases is a major problem in both shrimp farm and hatcheries and to control diseases, a number of antibiotics, sanitisers and chemicals are being used. This results in adverse environmental effects, emergence of antibiotic resistance and persistence of chemical residues in animal tissues. Considering the negative impact of antibiotics and other chemotherapeutants, biological contr...

متن کامل

Taking aim at targets.

population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol 2004; 33: 189–198 23. Yuyun MF, Khaw KT, Luben R et al. Microalbuminuria and stroke in a British population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. J Intern Med 2004; 255: 247–256 24. Harwell TS, Nelson RG, Little RR e...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Opinion in Microbiology

سال: 2007

ISSN: 1369-5274

DOI: 10.1016/j.mib.2007.08.002